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26 May 2010 Several scientific reports and commentaries Read more >>
Following a documentary on Ljungan virus on Swedish television SVT1 February 9 2009 T. Bergström and J.Å. Liljeqvist, two virologists from the University of Gothenburg wrote a critical commentary in the Swedish Läkartidningen (see Ljungan virus/Publications)
27 January 2010 Ljungan virus detected in bankvoles and yellow necked mice in norhtern Italy. Read more >>
28 October 2009 Positive effect of antiviral treatment in Ljungan virus diabetic animal-model Read more >>
Antiviral therapy normalizes the blood glucose level in Ljungan virus (LV) infected diabetic mice. Antiviral therapy also delayed onset of diabetes in type-1 diabetes-prone rats. These observations suggest that antiviral medicines may play a therapeutic role in diabetes.
A study from Karolinska Institutet in Stockholm, Sweden shows that the CD-1 mice infected early in life with LV develop a type-2-like diabetes later in life. Antibodies directed against LV and an antiviral medicine (Pleconaril) normalized the blood glucose level in these mice. The combination treatment of antibodies and antiviral medicine worked best. Antiviral therapy and antibody treatment also delayed the onset of disease in type 1 diabetes-prone rats. The results point to LV being an essential component in the development of diabetes in these animal models. The results also indicate that antiviral treatment may have the potential to play a very important role in treatment of diabetes. The results are presented in Microbiology and Immunology, 2009, Oct 53 (10) Pages 567 – 572.
12 May 2009 Sudden Infant Death Syndrome caused by Ljungan virus? Read more >>
Ljungan virus might be a major etiological agent in Sudden Infant Death Syndrome. This hypothesis is reported in the scientific journal Forensic Science, Medicine and Pathology.
30 Mars 2009 A new genotype of Ljungan virus has been discovered Read more >>
Analysis of a Ljungan virus isolated from a vole trapped in the USA indicates that recombination has occurred between related viruses during its evolution.
04 February 2009 Ljungan virus associated with human malformations Read more >>
Ljungan virus (LV) was found in cases of hydrocephaly and anencephaly when examined by immunohistochemistry and PCR. The association of LV with hydrocephaly and anencephaly suggests that LV may be playing an important role in central nervous system malformations in humans.
23 January 2009 Ljungan virus found in cases of intrauterine fetal death Read more >>
Tissues from cases of intrauterine fetal death have been found positive for Ljungan virus using two independent diagnostic techniques.
18 January 2009 Fetal death persists in Ljungan virus infected mice Read more >>
Laboratory mice infected with Ljungan virus (LV) early in pregnancy suffer from perinatal death. A recent study shows that female mice infected with LV continue to suffer from perinatal death during repeated pregnancies. Scientists from the Karolinska Institutet followed mice during six months and the results are presented in Birth Defects Research (Part B)
26 June 2008 New PCR test developed by the CDC Read more >>
A new real time PCR-assay for diagnosis of Ljungan virus and other Parecho viruses has been developed by the CDC. This new assay adds to the growing number of diagnostic tools recently developed.
20 April 2008 New diagnostic tools available Read more >>
A research group at Kalmar University has successfully made Ljungan virus protein specific antibodies. These antibodies can be used in the diagnosis of Ljungan virus infection. Details of these novel reagents are presented in the Journal of Virological Methods.
28 January 2008 The Ljungan virus studied in cell culture Read more >>
The replication and growth of the Ljungan virus have been studied in cell culture. The results, published in the scientific journal Virus Research, could help scientists to understand how the Ljungan virus is spread between different cells in an organ.
16 January 2008 A distant relative of the Ljungan virus found among Alaskan seals Read more >>
A completely new picorna virus has recently been isolated from wild seals. Analysis of the virus genome has determined that this new virus is a distant relative of the Ljungan virus. The results are published in the Journal of Virology by American and Canadian scientists.
10 January 2008 The Ljungan virus causes both type 1 and type 2 diabetes in voles Read more >>
Wild voles that carry the Ljungan virus show signs of both type 1 and type 2 diabetes. This is clear from a study conducted by Martin Blixt at Uppsala University. The results, indicating that the Ljungan virus may cause both types of diabetes, was published in the scientific journal General and Comparative Endocrinology.
02 August 2007 Unexpected find in diabetes infected laboratory rat Read more >>
The renowned “diabetes rat”, involved in more than a thousand scientific studies, carries the so called Ljungan virus. The discovery was made by a research team from Sweden, USA, and Germany. If scientists would also be able to cure the rat, this would be a major step towards the ability to treat and prevent diabetes in humans.
01 June 2007 Ljungan virus causes fetal deaths among pregnant women Read more >>
The Ljungan virus may cause previously unexplained cases of foetal death in humans. This is the conclusion of a Swedish-American pilot study, where evidence has been found of Ljungan virus infection in children that have died during late pregnancy. The results are published in the scientific journal Birth Defects Research.
News
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26 May 2010
Several scientific reports and commentaries
... >>
27 January 2010
Ljungan virus detected in bankvoles and yellow necked mice in norhtern Italy.
>>
28 October 2009
Positive effect of antiviral treatment in Ljungan virus diabetic animal-model
... >>
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